食品伙伴網(wǎng)訊  2020年3月27日，歐盟食品安全局（EFSA）發(fā)布消息，應歐盟委員會要求，歐盟膳食產(chǎn)品、營養(yǎng)和過敏專家組（NDA）研究小組就咖啡C21與DNA 鏈斷裂保護的健康宣稱提供發(fā)表科學意見。

 

　　根據(jù)提供的數(shù)據(jù)，專家小組認為飲用咖啡C21與DNA 鏈斷裂保護這一因果關系沒有建立。所以在歐盟咖啡C21的食品中，不得標示咖啡C21可以保護DNA 鏈不斷裂的宣稱。部分原文報道如下：

 

　　Following an application from Tchibo GmbH submitted for authorisation of a health claim pursuant to Article 13（5） of Regulation （EC） No 1924/2006 via the Competent Authority of Germany, the EFSA Panel on Nutrition, Novel Foods and Food Allergens （NDA） was asked to deliver an opinion on the scientific substantiation of a health claim related to Coffee C21 and protection of DNA from strand breaks. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The food proposed by the applicant as the subject of the health claim is Coffee C21. The Panel considers that Coffee C21, a coffee standardised by its concentration of caffeoylquinic acids （CQA）， trigonelline and N‐methylpyridinium （NMP）， is sufficiently characterised in relation to the claimed effect. The Panel considers that the claimed effect, protection of DNA from strand breaks, is a beneficial physiological effect. Out of the two human intervention studies from which conclusion could be drawn, one study provides some evidence that daily consumption of Coffee C21 （750 mL/day） for 4 weeks decreases DNA strand breaks in habitual coffee drinkers after coffee withdrawal over the previous four weeks. However, the results of this study were not replicated in another study conducted under similar conditions in the same study centre. No studies performed in a different setting, from which conclusions could be drawn, were available. No evidence has been provided for a mechanism by which coffee （including Coffee C21） would reduce DNA damage in human cells by reducing DNA strand breaks. The Panel concludes that a cause and effect relationship has not been established between the consumption of Coffee C21 and protection of DNA from strand breaks.

 

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