據(jù)了解，這種6-植酸酶由里氏木霉CBS 146250產(chǎn)生。經(jīng)過(guò)評(píng)估，專家小組認(rèn)為在擬議的使用條件下，該添加劑對(duì)所有家禽物種和所有豬都是安全的。當(dāng)對(duì)于所有生長(zhǎng)中的家禽品種和所有豬以500 FTU/千克補(bǔ)充時(shí)，以及對(duì)于產(chǎn)蛋雞和其他產(chǎn)蛋鳥(niǎo)以300 FTU/千克補(bǔ)充時(shí)，該添加劑在提高磷利用率方面是有效的。部分原文報(bào)道如下：

 

　　Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 6-phytase produced by the genetically modified strain Trichoderma reesei CBS 146250 (Axtra® PHY GOLD 30L, Axtra® PHY GOLD 30 T and Axtra® PHY GOLD 65G) as a zootechnical feed additive for all poultry species and all pigs. The FEEDAP Panel concluded that the genetic modification of the production strain does not give rise to safety concerns. based on the no observed adverse effect level identified in a subchronic oral toxicity study in rats, the additive was considered safe for all poultry species and all pigs at the proposed conditions of use. The Panel also concluded that the use of the product as a feed additive does not give rise to concerns for consumers and the environment. Owing to the lack of data obtained with the final formulations, the Panel cannot conclude on the potential of the additive to be irritant to eyes or skin. Due to the proteinaceous nature of the active substance, it is considered a respiratory sensitiser. The panel concludes that the additive is efficacious in increasing the phosphorus utilisation when supplemented at 500 FTU/kg for all growing poultry species and all pigs, and at 300 FTU/kg in laying hens and other laying birds.

 

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