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    歐盟評估非轉(zhuǎn)基因地衣芽孢桿菌AE-TA生產(chǎn)的α-淀粉酶的安全性
    日期:2024-05-16  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2024年5月15日,歐盟食品安全局就一種α-淀粉酶(α-amylase)的安全性評價發(fā)布意見。
     
      據(jù)了解,這種食品酶是由非轉(zhuǎn)基因地衣芽孢桿菌AE-TA生產(chǎn)的,旨在用于八種食品制造過程。
     
      經(jīng)過評估,專家小組認(rèn)為,在預(yù)期的使用條件下,不能排除飲食暴露引起過敏反應(yīng)的風(fēng)險(生產(chǎn)蒸餾酒精除外),但這種可能性被認(rèn)為很低。根據(jù)所提供的數(shù)據(jù),評估小組得出結(jié)論,這種食品酶在預(yù)期使用條件下不會引起安全問題。部分原文報道如下:
     
      The food enzyme α-amylase (4-α-d-glucan glucanohydrolase; EC 3.2.1.1) is produced with the non-genetically modified microorganism Bacillus licheniformis strain AE-TA by Amano Enzyme Inc. The food enzyme is intended to be used in eight food manufacturing processes. Since residual amounts of food enzyme-total organic solids (TOS) are removed in two food manufacturing processes, dietary exposure was calculated only for the remaining six processes. It was estimated to be up to 0.056 mg TOS/kg body weight per day in European populations. The production strain of the food enzyme fulfils the requirements for the qualified presumption of safety approach to safety assessment. Consequently, in the absence of other concerns, the Panel considered that toxicological studies were not needed for the safety assessment of this food enzyme. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and two matches with respiratory allergens were found. The Panel considered that the risk of allergic reactions upon dietary exposure to this food enzyme cannot be excluded (except for the production of distilled alcohol), but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
     
      本文由食品伙伴網(wǎng)食品資訊中心編輯,有任何疑問,請聯(lián)系news@foodmate.net。
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