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    歐盟評估一種6-植酸酶作為所有家禽、豬及有鰭魚類飼料添加劑的安全性和有效性
    日期:2024-03-12  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2024年3月11日,據(jù)歐盟食品安全局EFSA)消息,應歐盟委員會要求,歐盟動物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就一種6-植酸酶(6-phytase)作為所有家禽、豬及有鰭魚類飼料添加劑的安全性和有效性發(fā)表科學意見。
     
      據(jù)了解,這種6-植酸酶是由米曲霉DSM 33737生產(chǎn)的。經(jīng)過評估,專家小組認為在建議的使用條件下該添加劑對目標物種、消費者和環(huán)境是安全的。由于缺乏足夠的數(shù)據(jù),評估小組無法就添加劑對產(chǎn)蛋和繁殖家禽以及生長豬的功效得出結論。部分原文報道如下:
     
      Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 6-phytase produced by the genetically modified strain Aspergillus oryzae DSM 33737 (HiPhorius 10, 40, 20L and 50L) as a zootechnical feed additive for all poultry, all Suidae and all fin fish. The FEEDAP Panel concluded that the genetic modification of the production strain does not give rise to safety concerns. based on the no observed adverse effect level identified in a subchronic oral toxicity study in rats, the additive was considered safe for all poultry, all Suidae and all fin fish at the proposed conditions of use. The Panel also concluded that the use of the product as a feed additive is of no concern for the consumers and the environment. The liquid formulations of the additive are not skin or eye irritants. The two solid ones are not skin irritants but are eye irritants. Owing to the lack of data, the Panel cannot conclude on the skin sensitisation of the final formulations of the additive. Due to the proteinaceous nature of the active substance (6-phytase), the additive is considered a respiratory sensitiser. The Panel concludes that the additive is efficacious when included in the diet of poultry for fattening or reared for laying/breeding, reproductive Suidae, and all fin fish. Due to the lack of sufficient data, the Panel could not conclude on the efficacy for laying and reproductive poultry and growing Suidae.
     
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