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    歐盟評(píng)估一種1,4-α-葡聚糖分支酶的安全性
    日期:2023-02-23  來(lái)源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2023年2月22日,歐盟食品安全局就一種食品酶1,4-α-葡聚糖分支酶(1,4-α-glucan branching enzyme)的安全性評(píng)價(jià)發(fā)布意見(jiàn)。
     
      據(jù)了解,這種食品酶是由非轉(zhuǎn)基因嗜熱脫氮芽孢桿菌(Geobacillus thermodenitrificans)菌株TRBE14生產(chǎn)的,旨在用于谷物加工、烘焙加工以及肉類和魚類加工中。
     
      經(jīng)過(guò)評(píng)估,專家小組指出,該食品酶含有溶菌酶,是一種已知的過(guò)敏原。因此,不能排除致敏性。根據(jù)所提供的數(shù)據(jù),小組得出結(jié)論,該食品酶在預(yù)期的使用條件下不會(huì)引起安全問(wèn)題。部分原文報(bào)道如下:
     
      The food enzyme 1,4-α-glucan branching enzyme ((1–4)-α-d-glucan:(1–4)-α-d-glucan 6-α-d-[(1–4)-α-d-glucano]-transferase; EC 2.4.1.18) is produced with the non-genetically modified Geobacillus thermodenitrificans strain TRBE14 by Nagase (Europa) GmbH. The production strain has been shown to qualify for the qualified presumption of safety (QPS) approach. The food enzyme is intended to be used in cereal-based processes, baking processes as well as meat and fish processing. Dietary exposure to the food enzyme–total organic solids (TOS) was estimated to be up to 0.29 mg TOS/kg body weight (bw) per day in European populations. Toxicological studies were not considered necessary given the QPS status of the production strain and the nature of the manufacturing process. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel noted that the food enzyme contains lysozyme, a known allergen. Therefore, allergenicity cannot be excluded. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use.
     
      本文由食品伙伴網(wǎng)食品資訊中心編輯,供網(wǎng)友參考,有任何疑問(wèn),請(qǐng)聯(lián)系news@foodmate.net。
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