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    歐盟評估XAP 104 TPT作為育肥雞等家禽飼料添加劑的安全性和有效性
    日期:2020-07-01  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2020年6月29日,應(yīng)歐盟委員會要求,歐盟動物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就XAP 104 TPT作為育肥雞、蛋雞和小型家禽飼料添加劑的安全性和有效性發(fā)布科學意見。
     
      經(jīng)過評估,專家小組無法就添加劑XAP 104 TPT對目標物種、消費者和使用者的安全性得出結(jié)論。而該添加劑對育肥雞是有效的,由于缺乏足夠的數(shù)據(jù),評估小組無法就添加劑對蛋雞的功效得出結(jié)論。部分原文報道如下:
     
      Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on the safety and efficacy of Axtra XAP 104 TPT as a zootechnical feed additive (digestibility enhancers) for poultry species. The additive contains three enzyme activities (endo‐1,4‐beta‐xylanase, protease and alpha‐amylase) produced by three different genetically modified strains. Viable cells and recombinant DNA of the strains producing the protease and amylase were not detected in the final product. Owing to the insufficient data, uncertainty remained on the presence in the additive of viable cells of the strain producing the xylanase. The results obtained in the genotoxicity and subchronic oral toxicity studies performed with the three fermentation products did not indicate safety concerns resulting from the fermentation products used in the formulation/manufacturing. However, uncertainties remain on the suitability of the test item used in the studies conducted with the xylanase; therefore, the Panel was not in the position to conclude on the toxicological potential of AXTRA  XAP 104 TPT . Consequently, the Panel could not conclude on the safety of the additive for the target species, consumers and users. Owing to the uncertainty on the presence of viable cells of one of the production strains in the additive, the Panel could not conclude on the safety for the environment. The FEEDAP Panel concluded that AXTRA  XAP 104 TPT is efficacious in chickens for fattening, chickens reared for laying and minor poultry species up to the point of lay at the level of 2,000 U xylanase, 200 U amylase and 4,000 U protease per kg feed. Owing to the lack of sufficient data, the Panel could not conclude on the efficacy of the additive for laying hens.
     
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