食品伙伴網(wǎng)訊  2019年8月12日，據(jù)歐盟食品安全局（EFSA）消息，應(yīng)歐盟委員會要求，歐盟動物飼料添加劑和產(chǎn)品（FEEDAP）研究小組就β-1,4-內(nèi)切木聚糖酶（endo‐1,4‐β‐xylanase（RONOZYME®WX CT/LE））作為母豬繁殖飼料添加劑的安全性和有效性發(fā)表科學(xué)意見。

 

　　據(jù)了解，該添加劑含有的β-1,4-內(nèi)切木聚糖酶是由一種轉(zhuǎn)基因米曲霉（Aspergillus oryzae） 生產(chǎn)的。

 

　　部分原文報道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed （FEEDAP） was asked to deliver a scientific opinion on the safety and efficacy of RONOZYME® WX CT/L as a feed additive for sows for reproduction. This additive contains endo‐1,4‐β‐xylanase produced by a genetically modified strain of Aspergillus oryzae and it is authorised in the EU as a feed additive for poultry for fattening, weaned piglets and pigs for fattening. The applicant requests the extension of use of the additive to sows for reproduction at 200 FXU/kg feed. The FEEDAP Panel concluded that there are no concerns for consumer safety and no risks for the environment are expected from the use of RONOZYME®  WX in sows. The FEEDAP Panel concluded that the additive is not a skin or eye irritant, but it should be considered a respiratory sensitiser, but could not conclude on the skin sensitisation potential of the additive. A tolerance trial in lactating sows and two toxicological studies were made available to support the safety of the target species. based on the data available, the FEEDAP Panel concluded that the additive is safe for sows for reproduction at the recommended level with a wide margin of safety. Three efficacy studies in lactating sows were evaluated. Sows that received RONOZYME® WX showed improvements on the apparent faecal digestibility of the energy in the three trials. The enzyme activity in feed that showed efficacy ranged from 124 to 287 FXU/kg feed, and the FEEDAP Panel concluded that the additive has the potential to be efficacious as a zootechnical additive in lactating sows at a level of approximately 250 FXU/kg feed. No data has been provided in gestating sows, and consequently, the Panel could not conclude on this physiological stage of the productive cycle.

 

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