食品伙伴網(wǎng)訊  應(yīng)歐盟委員會(huì)的要求，歐盟食品安全局食品添加劑和營(yíng)養(yǎng)源專(zhuān)家組（ANS）重新評(píng)估了氯化亞錫和二水氯化亞錫（stannous chloride）作為食品添加劑的安全性。

 

    從監(jiān)管最高水平暴露評(píng)估方案來(lái)看，氯化亞錫作為食品添加劑時(shí)，所有年齡組的平均每日暴露使用量均低于1.3微克/千克體重，氯化亞錫暴露的第95百分位范圍為每天0.0微克/千克體重至成人每天11.2微克/千克體重。通過(guò)動(dòng)物實(shí)驗(yàn)發(fā)現(xiàn)，胃腸道吸收氯化亞錫的量很低，歐盟專(zhuān)家小組得出結(jié)論認(rèn)為，氯化亞錫在目前的授權(quán)使用水平中不存在安全問(wèn)題。

 

    部分原文如下：

 

    The Panel on Food Additives and Nutrient Sources added to Food （ANS） provides a scientific opinion re‐evaluating the safety of stannous chloride and stannous chloride dihydrate （E 512） as food additives. The Panel considered that adequate exposure and toxicity data were available. Stannous chloride is only permitted as food additives in one food category and no reply on the actual use level of stannous chloride （E 512） as a food additive and on its concentration in food was provided by any interested party. According to the Mintel's Global New Products Database （GNPD）， stannous chloride was not labelled on any products in the EU nor in Norway. The regulatory maximum level exposure assessment scenario is based on the maximum permitted levels （MPLs） for stannous chloride （E 512）， which is 25 mg Sn/kg. The mean exposure to stannous chloride （E 512） from its use as a food additive was below 1.3 μg Sn/kg body weight （bw） per day for all age groups. The 95th percentile of exposure to stannous chloride （E 512） ranged from 0.0 μg Sn/kg bw per day in all groups to 11.2 μg Sn/kg bw per day in adults. Absorption of stannous chloride from the gastrointestinal tract is low there is no concern with respect to carcinogenicity and genotoxicity. Gastrointestinal irritation was reported in humans after ingestion of a bolus dose of 40 mg Sn. The Panel concluded that stannous chloride （E 512） is of no safety concern in this current authorised use and use levels.

 

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