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    當(dāng)前位置: 首頁 » 食品資訊 » 外訊導(dǎo)讀 » 歐盟評估擴(kuò)展使用非轉(zhuǎn)基因熱解蛋白無氧芽孢桿菌菌株AE-TP生產(chǎn)的嗜熱菌蛋...

    歐盟評估擴(kuò)展使用非轉(zhuǎn)基因熱解蛋白無氧芽孢桿菌菌株AE-TP生產(chǎn)的嗜熱菌蛋白酶的安全性

    放大字體  縮小字體 時(shí)間:2024-07-25 11:29 來源:食品伙伴網(wǎng) 作者: 澤夕   
    核心提示:2024年7月24日,歐盟食品安全局就一種食品酶嗜熱菌蛋白酶(thermolysin)的安全性評價(jià)發(fā)布意見。
       食品伙伴網(wǎng)訊  2024年7月24日,歐盟食品安全局就一種食品酶嗜熱菌蛋白酶(thermolysin)的安全性評價(jià)發(fā)布意見。
     
      據(jù)了解,這種食品酶是由非轉(zhuǎn)基因熱解蛋白無氧芽孢桿菌菌株AE-TP生產(chǎn)的,旨在用于7種食品生產(chǎn)過程。
     
      經(jīng)過評估,專家小組得出結(jié)論,這種食品酶在預(yù)期使用條件下不會引起安全問題。部分原文報(bào)道如下:
     
      The food enzyme glucan 1,4-α-glucosidase (4-α-d-glucan glucohydrolase; EC 3.2.1.3) is produced with the non-genetically modified Rhizopus arrhizus strain AE-G by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in one food manufacturing process. Subsequently, the applicant requested to extend its use to nine additional processes and revised the use levels. In this assessment, EFSA updated the safety evaluation of this food enzyme for uses in a total of 10 food manufacturing processes. As the food enzyme–total organic solids (TOS) is removed from the final foods in two food manufacturing processes, the dietary exposure to the food enzyme–TOS was estimated only for the remaining eight processes. Dietary exposure was up to 0.424 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1868 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 4406. based on the data provided for the previous evaluation and the margin of exposure revised in the present evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
     
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    日期:2024-07-25
     
     
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