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    歐盟評(píng)估伏馬菌素酯酶作為所有動(dòng)物飼料添加劑的安全性和有效性
    日期:2020-07-20  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2020年7月20日,據(jù)歐盟食品安全局EFSA)消息,應(yīng)歐盟委員會(huì)要求,歐盟動(dòng)物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就伏馬菌素酯酶(fumonisin esterase)作為所有動(dòng)物飼料添加劑的安全性和有效性發(fā)表科學(xué)意見。
     
      據(jù)了解,伏馬菌素酯酶是由Komagataella phaffii DSM 32159制成的添加劑,旨在降解飼料污染物中的伏馬菌素霉菌毒素。經(jīng)過評(píng)估,專家小組認(rèn)為在建議的使用條件下該添加劑對(duì)目標(biāo)物種、消費(fèi)者和環(huán)境是安全的。當(dāng)以最低建議劑量40 U / kg飼料使用時(shí),該添加劑具有降解發(fā)酵飼料中的伏馬毒素的能力(伏馬毒素的含量在歐盟規(guī)定的指導(dǎo)范圍內(nèi))。專家小組指出,僅在青貯飼料中才顯示出功效,而在其他發(fā)酵飼料(如液體飼料)中卻沒有顯示出這種功效。部分原文報(bào)道如下:
     
      Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on the safety and efficacy of fumonisin esterase from Komagataella phaffii DSM 32159 as a technological feed additive for all animal species. The product has been already assessed by the FEEDAP Panel for use in pigs and poultry feed as technological additive and was granted with an authorisation in the EU for this use. In the current application, the additive is intended to be used in fermenting feeds with the purpose to reduce the contamination of feed by fumonisins. New data provided showed that no recombinant DNA could be detected in three batches of the product. The evidence provided – based on the data submitted in the previous and the current application – allowed the FEEDAP Panel to conclude that the additive is safe for the target animals under the proposed conditions of use. The Panel also considered valid the previous conclusions in which the safety of the additive for consumers and the environment was established. The additive is not toxic by inhalation and the respiratory exposure is likely to be low; however, a risk of sensitisation via the respiratory route cannot be excluded. The additive is non‐irritant to skin and eyes and is not considered as a dermal sensitiser. The additive has the capacity to degrade fumonisins in fermenting feed (with a fumonisin content within the guidance limits operating in the EU ) when used at the minimum recommended dose of 40 U/kg feed. The FEEDAP Panel notes that the efficacy has been demonstrated only in silages, not in other fermenting feeds like e.g. liquid feeds.
     
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