歐盟專家組認為，現(xiàn)有數(shù)據(jù)并未發(fā)現(xiàn)兩類物質(zhì)的遺傳毒性，而且針對小鼠與大鼠的致癌性研究也呈現(xiàn)陰性。在現(xiàn)有數(shù)據(jù)基礎(chǔ)上，不能改變針對兩種物質(zhì)的每日建議攝入量。
部分原文報道如下：
The Panel on Food Additives and Nutrient Sources added to Food （ANS） provided a scientific opinion re-evaluating the safety of sodium nitrate （E 251） and potassium nitrate （E 252） when used as food additives. The current acceptable daily intakes （ADIs） for nitrate of 3.7 mg/kg body weight （bw） per day were established by the SCF （1997） and JECFA （2002）。 The available data did not indicate genotoxic potential for sodium and potassium nitrate. The carcinogenicity studies in mice and rats were negative. The Panel considered the derivation of an ADI for nitrate based on the formation of methaemoglobin, following the conversion of nitrate, excreted in the saliva, to nitrite.
